Overdose' -acetylcysteine should always be given without delay (the nomogram When ingestion has occurred over a period of one hour or more - 'staggered where there is doubt over the timing of paracetamol ingestion including.

On a new treatment nomogram, regardless of risk factors for hepatotoxicity Treatment line joining points of 100 mg/L at 4 hours and 15 mg/L at 15 hoursĪfter ingestion should receive acetylcysteine (Parvolex or generics) based

all patients with a timed plasma paracetamol level on or above a single.

Simplified guidance on treating paracetamol overdose with intravenous acetylcysteine

2 would die of liver failure if untreated.

10 consume enough drug to cause liver damage.naloxone may quickly reverse the opiate component. In adults, doses of more than 250 mg / kg of paracetamol may cause severe toxicity, the main complication of which, is liver damage.ĭeaths are more frequent when the drugs are a mixture, particularly, if the other is an opiate. Paracetamol poisoning is common both alone and mixed with another drug such as co-proxamol.

Overdose paracetamol antidote